PhD Position

Department of Pediatric Research, Oslo University Hospital

Sognsvannsveien 20, 0372 Oslo

Forskningsjobber i Oslo

søknader: 8 søknader
visninger: 95 visninger
Frist: Frist: 15.11.20263 dager igjen

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Stillingsbeskrivelse

The Department of Pediatric Research at Oslo University Hospital (OUS) is seeking a highly motivated candidate for a 3-year, 100% PhD position. The project, funded by the South-Eastern Norway Regional Health Authority, focuses on investigating the mechanisms of neonatal cholestasis and pruritus using liver organoids derived from disease-specific induced pluripotent stem cells (iPSC).

About the role

As a PhD candidate, you will work under the supervision of Professor Runar Almaas, alongside co-supervisor Barbora Smolkova and senior researcher Gareth Sullivan. Your primary responsibilities will involve designing, planning, and performing experiments using iPSC-derived liver organoids to study protein trafficking, the effects of modulating factors, and potential new treatments.

Key responsibilities

Develop and utilize liver organoid models to mimic human liver disease.
Conduct molecular biology experiments, including protein trafficking analysis and drug testing.
Collaborate effectively within an international research team of scientists and engineers.
Document and present research findings in a structured and scientific manner.

Qualifications

Master’s degree (or equivalent) in medicine, biomedicine, biotechnology, or molecular biology.
Strong practical skills in nucleic acid extraction, quantification, and analysis (e.g., qRT-PCR, ddPCR, Western blotting).
Experience with cell cultivation and handling is highly advantageous.
Knowledge of molecular techniques such as CRISPR/Cas9 gene editing or next-generation sequencing is a plus.
Excellent written and oral communication skills in English.

What we offer

We offer a 3-year full-time position in a friendly, international, and ambitious research environment. You will receive training in advanced methods and models, benefit from dedicated supervision, and enjoy favorable pension and welfare arrangements at Oslo University Hospital.

For further information, please contact Head of Department Runar Almaas at +47 41321932.

Krav

Master’s degree in medicine, biomedicine, biotechnology, or molecular biology.
Practical experience with nucleic acid analysis and protein techniques like Western blotting.
Strong interest in scientific research and innovative experimental design.
Ability to work both independently and as part of a research team.
Proficiency in English, both written and oral.

Ferdigheter

Molecular biologyCell cultivationLiver organoidsiPSC technologyqRT-PCRWestern blottingScientific writing

Lønn

580 000 kr per år

Estimert lønn. Kan avvike fra lønnen arbeidsgiver tilbyr.

Erfaring

junior

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