PhD Research Fellow position

About the job

Oslo University Hospital (OUS) is seeking a PhD Research Fellow to work on innovative approaches to treating glioblastoma multiforme (GBM), one of the most lethal human cancers. This is a 3-year position within the Translational Research Unit at the Section for Cellular Therapy, focusing on combining immunotherapy with radiotherapy to improve treatment outcomes.

Responsibilities

• Produce and profile GD2-specific CAR T cells in 2D and 3D tumour cell cultures.
• Establish orthotopic in vivo models to monitor tumour growth and test CAR T-cell efficiency in combination with radiotherapy and other immunotherapies.
• Analyse tumours for immunogenic cell death (ICD), changes in the tumour microenvironment, and T-cell dynamics.
• Collaborate with other InnovaRTBRAIN partners, including a secondment at institutions in Italy and Spain.
• Conduct in vivo experiments, including surgery, and use techniques such as flow cytometry, immunohistochemistry, and molecular cloning.

Qualifications

• A 5-year Master’s degree in biology, immunology, biotechnology, or a related field.
• Experience with cellular biology (cell culture, cell transfection, molecular biology techniques such as DNA manipulation and cloning).
• Strong theoretical knowledge of immunology.
• Ability to perform in vivo experiments, including surgery.
• Knowledge of techniques such as flow cytometry, ELISA, primary T-cell culture, western blot, and protein work is an advantage.

Personal qualities

• Attention to detail and strong organizational skills.
• Dynamism, reactivity, and autonomy.
• Excellent written English skills and the ability to summarize complex information.
• Flexibility and the ability to work effectively in a team.

We offer

• Enrolment in a PhD program.
• An international work environment with opportunities for skill development and innovation within a competent team.
• An attractive 36-month salary.
• Comprehensive training in scientific and transferable skills, including open science, responsible research and innovation, ethics, data management, entrepreneurship, communication, and gender balance in science.

How to apply

Applications must include a motivation letter (max. 1 page), CV with education, work experience, language skills, and at least two referees with email addresses, a certified copy of a recent transcript of exams, a certified copy of a Master of Science certificate or a letter from the Head of the degree course stating that the student will complete the degree before February 2027, and a summary of technical skills and their context of use (max. 1 page).

All applications will be checked for eligibility, particularly adherence to the mobility rule. Incomplete, overly long, or AI-generated applications will not be considered. Shortlisted candidates will be invited for an interview, and candidates will be notified of the outcome as soon as possible. The start of employment is foreseen for March 2027.

Contact

For more information, please contact the main supervisors: Else Marit Inderberg and Sébastien Wälchli at Oslo University Hospital.