Researcher

Researcher

A 2-year position as a researcher is available at the Centre for Advanced Cell Therapy (ACT), Oslo University Hospital, under the supervision of the ACT Director Anna Pasetto. The position will be located at the pre-GMP facility at the Norwegian Radium Hospital, Oslo.

The ACT Centre is a core facility and translational research environment dedicated to accelerating the development and clinical implementation of advanced cell therapies. We are looking for a highly motivated candidate with a strong interest in translational cell therapy, process development, and quality control methods for advanced therapy medicinal products.

About the project

The successful candidate will work on the optimization and development of manufacturing and quality control processes for cell therapy products. The project will involve the development, testing, and implementation of new protocols for cell therapy manufacturing, analytical characterization, and potency/functionality assessment. A key focus will be the introduction and evaluation of automated solutions for manufacturing and QC workflows, in close collaboration with national and international academic and industry partners.

Main tasks

• Develop and optimize manufacturing protocols for cell therapy products, including T cells, NK cells, iPSC-derived products, or related cell platforms.
• Establish and validate analytical methods for cell therapy process development.
• Perform advanced cell culture, expansion, activation, differentiation and genetic modification workflows.
• Design and perform functionality assays relevant to cell therapy products.
• Use multiparameter flow cytometry for phenotypic and functional characterization.
• Apply molecular biology methods and contribute to the evaluation and implementation of automated systems for manufacturing and QC.
• Collaborate with industry partners and multidisciplinary teams.
• Contribute to documentation, reporting, publication of results, and preparation of protocols.