Researcher in CRISPR gene therapy group

Researcher in CRISPR gene therapy group

We announce an 80%, one-year extendable researcher position in the CRISPR gene therapy group led by Emma Haapaniemi to be based at NCMBM, University of Oslo & Oslo University Hospital. We welcome applications both from recent PhD graduates and more experienced scientists.

The successful candidate will join a highly integrated and motivated team with diverse skills and expertise across molecular biology and immunology. The work tasks will concentrate on optimizing and scaling up protocols for efficient mutation correction in human T cells and hematopoietic stem cells utilizing CRISPR-Cas9 gene editing technologies.

Work tasks:

• Design and conduct custom CRISPR experiments and screens in high-throughput robotics platforms.
• Set up custom Next Generation Sequencing libraries and technologies.
• Set up functional assays for immune cells.
• Supervise students and technicians in designing and conducting molecular biology experiments.

About the laboratory:

The aim of the Haapaniemi group is to build a gene editing platform that can be used to correct patient-specific mutations in ex vivo cell therapies for genetic immune and other rare childhood diseases. We use high-throughput biology techniques to optimize, develop and understand the CRISPR-Cas9 system and develop methods to evaluate its safety in a clinical setting.